Dim instance As IAdvancedFilterTarget
Dim context As FilterContext
Dim intermediateNodeId As NodeId
Dim sourceTypeId As NodeId
Dim targetTypeId As NodeId
Dim referenceTypeId As NodeId
Dim hops As Integer
Dim includeTypeDefintionSubtypes As Boolean
Dim includeReferenceSubtypes As Boolean
Dim value As Boolean
 
value = instance.IsRelatedTo(context, intermediateNodeId, sourceTypeId, targetTypeId, referenceTypeId, hops, includeTypeDefintionSubtypes, includeReferenceSubtypes)

bool IsRelatedTo( 
   FilterContext context,
   NodeId intermediateNodeId,
   NodeId sourceTypeId,
   NodeId targetTypeId,
   NodeId referenceTypeId,
   int hops,
   bool includeTypeDefintionSubtypes,
   bool includeReferenceSubtypes
)